Ma'anar ƙamus na hypersensitivity wani ƙari ne ko rashin daidaituwa na tsarin rigakafi zuwa abin ƙarfafawa, kamar allergen ko wani abu na waje. Wannan na iya bayyana azaman alamu kamar itching, kumburi, rash, amya, wahalar numfashi, ko anaphylaxis. Ana iya rarraba rashin jin daɗi zuwa nau'i daban-daban dangane da hanyoyin rigakafin da ke tattare da su, irin su nau'in I (nau'i na gaggawa), nau'in II (hypersensitivity na cytotoxic), nau'in III (cututtukan ƙwayar cuta), da nau'in IV (jinkirin hypersensitivity). Hakanan za'a iya amfani da kalmar a fili don kwatanta martanin da ya wuce kima ko wuce gona da iri ga kowane irin kuzari, ba wai kawai yana da alaƙa da tsarin rigakafi ba.