Inombolo eyinhloko iyinombolo ephozithivu enkulu kuno-1 engenakho ukuhlukanisa inombolo eqondile ngaphandle kuka-1 kanye nayo uqobo. Ngamanye amazwi, inombolo eyinhloko iyinombolo ehlukaniseka kuphela ngu-1 futhi ngokwayo. Izibonelo zezinombolo eziyinhloko zifaka u-2, 3, 5, 7, 11, 13, 17, 19, 23, 29, 31, 37, 41, njalonjalo. Izinombolo eziyinhloko zidlala indima ebalulekile kwizibalo futhi zisetshenziswa ezinhlelweni eziningi, okuhlanganisa i-cryptography kanye nethiyori yezinombolo.