Propylthiouracil (PTU) magani ne da ake amfani da shi don magance hyperthyroidism (overactive thyroid) ta hanyar rage adadin hormone thyroid da glandon thyroid ke samarwa. Yana aiki ta hanyar hana samar da hormone thyroid ta hanyar toshe aikin wani enzyme da ake kira thyroperoxidase, wanda ke da hannu a cikin kira na hormone thyroid. Baya ga amfani da shi wajen maganin hyperthyroidism, ana kuma iya amfani da PTU don shirya marasa lafiya don aikin tiyatar thyroid ko maganin iodine na rediyoaktif.