Ma'anar ƙamus na kalmar "Immunoglobulin E" ko "IgE" wani nau'i ne na furotin, wanda kuma aka sani da antibody, wanda ke taka muhimmiyar rawa a cikin martanin tsarin rigakafi ga allergens da cututtuka na parasitic. Kwayoyin rigakafi na musamman da aka sani da ƙwayoyin plasma suna samar da IgE kuma ana samun su a cikin jini da kyallen jikin jiki. IgE antibodies. Waɗannan ƙwayoyin rigakafi suna ɗaure ga masu karɓa akan ƙwayoyin mast da basophils, waɗanda nau'ikan ƙwayoyin rigakafi ne waɗanda ke sakin histamine da sauran sinadarai don amsawa ga allergens. Wannan sakin histamine yana haifar da alamun rashin lafiyan jiki, kamar itching, kumburi, da kumburi. helminths (tsutsotsi). IgE antibodies suna ɗaure ga waɗannan ƙwayoyin cuta kuma suna kunna ƙwayoyin rigakafi don lalata su.