Ma'anar ƙamus na kalmar "hypercholesterolemia" yanayi ne na likitanci wanda ke da yawan adadin cholesterol a cikin jini. Yana da wani nau'i na hyperlipidemia, wanda ke nufin yawan matakan lipids (fats) a cikin jini, kuma yana iya zama haɗari ga matsalolin kiwon lafiya daban-daban kamar cututtukan zuciya, bugun jini, da cututtukan jijiya. Hypercholesterolemia na iya haifar da shi ta hanyar abubuwan halitta, abubuwan rayuwa kamar abinci da motsa jiki, da sauran yanayin kiwon lafiya. Yawanci ana gano shi ta hanyar gwajin jini wanda ke auna matakan cholesterol.