Ma'anar ƙamus na kalmar "megacolon na haihuwa" yanayi ne na likita wanda yake da babban hanji wanda ba ya aiki yadda ya kamata. Hakanan ana kiranta da cutar Hirschsprung, wacce ba kasafai ake samun haihuwa ba inda kwayoyin jijiyoyi a cikin babban hanji suka ɓace, wanda ke haifar da rashin iya wucewa ta al'ada. Halin yana samuwa a lokacin haihuwa kuma yana iya haifar da alamu kamar maƙarƙashiya, ciwon ciki, da amai. Magani yawanci yakan haɗa da tiyata don cire ɓangaren hanji da abin ya shafa.