Botulism toxin (wanda kuma aka sani da botulinum toxin) wani ƙaƙƙarfan neurotoxin ne wanda ƙwayoyin cuta Clostridium botulinum ke samarwa. Wannan guba na iya haifar da mummunar cuta mai haɗari kuma mai yuwuwar cutar da ake kira botulism lokacin da aka sha, shaka, ko shanye ta cikin rauni. Botulism toxin yana aiki ta hanyar toshe sakin wani neurotransmitter da ake kira acetylcholine, wanda zai iya haifar da gurɓataccen tsoka, gazawar numfashi, da mutuwa. Duk da haka, a cikin ƙananan allurai, ana amfani da toxin botulism don dalilai na warkewa, kamar a cikin maganin ƙwayar tsoka, ciwon kai, da yawan gumi.