Kalmar "anticholinergic" tana nufin rukuni na kwayoyi ko abubuwan da ke toshe ayyukan neurotransmitter acetylcholine a cikin tsarin juyayi. Ana amfani da waɗannan magungunan don yanayin kiwon lafiya iri-iri, kamar cutar Parkinson, mafitsara mai yawan aiki, da kuma cututtukan huhu na huhu (COPD). toshe acetylcholine a cikin jiki, kamar rage gumi, bushe baki, da maƙarƙashiya. Wadannan illolin na iya faruwa a matsayin illar wasu magunguna ko kuma daga kamuwa da abubuwa masu guba, kamar wasu tsirrai ko namomin kaza.