Kalmar "adrenergic" tana da alaƙa da ko shafar tsarin juyayi mai juyayi, wanda ke amfani da adrenaline neurotransmitter (wanda aka fi sani da epinephrine) don kunna martani daban-daban a cikin jiki. Magungunan Adrenergic ko mahadi suna kwaikwaya ko haɓaka tasirin adrenaline akan kyallen jikin jiki da gabobin jiki, kamar ƙara yawan bugun zuciya, hawan jini, da sakin glucose daga hanta. Kalmar kuma tana iya komawa ga masu karɓa waɗanda ke ɗaure adrenaline da mahadi masu alaƙa a cikin jiki, irin su alpha da beta adrenergic receptors.