Giovanni de' Medici ma'aikacin banki ne na Italiya kuma ɗan siyasa wanda ya rayu a zamanin Renaissance. Ya kasance memba na dangin Medici, wanda yana ɗaya daga cikin mafi arziki kuma iyalai masu tasiri a Florence, Italiya. Giovanni de' Medici ɗan Cosimo de' Medici ne, kuma an haife shi a shekara ta 1421. Ya zama shugaban iyali bayan mutuwar mahaifinsa a shekara ta 1464 kuma ya taka muhimmiyar rawa a siyasar Florence. An kuma san shi da goyon bayan fasaha, ciki har da ƙaddamar da ayyuka daga shahararrun masu fasaha irin su Sandro Botticelli da Michelangelo.