Yakin Wake yana nufin wani hatsaniya na soji da aka yi a tsibirin Wake na tekun Pacific a lokacin yakin duniya na biyu. An gwabza yakin tsakanin Amurka da Japan a watan Disamba na shekarar 1941, jim kadan bayan harin da aka kai kan Pearl Harbor. Sojojin kasar Japan sun kai farmaki a tsibirin, wanda wasu ‘yan tsirarun sojojin ruwa da na ruwa na Amurka suka kare. Duk da cewa an fi su da yawa kuma ba su da bindiga, masu tsaron Amurka sun yi yaƙi da jajircewa, inda suka yi hasarar babbar asara ga sojojin Japan kafin daga bisani su ci nasara. Yaƙin Wake ana ɗaukarsa a matsayin muhimmin farkon shiga gidan wasan kwaikwayo na Pacific na Yaƙin Duniya na II.