Yaƙin St. Mihiel yaƙin duniya na ɗaya ne da aka yi tsakanin 12-15 ga Satumba, 1918, a yankin Lorraine na ƙasar Faransa. An gwabza yakin ne tsakanin sojojin kawance musamman Amurka da Faransa da kuma daular Jamus. Makasudin yakin shine a keta layin Jamus kuma a dauki kagara na St. Mihiel. Yakin ya yi nasara ga kawancen, inda aka karya layukan Jamus, aka kuma kame garin St. Mihiel. Yana daya daga cikin manyan hare-hare masu cin gashin kansu na farko da Amurka ta kaddamar a lokacin yakin duniya na daya.