TV series example of the word

The Big Bang Theory Season 12, Episode 23
means... positive?

The Big Bang Theory Season 9, Episode 14
I think what Sheldon means to say,

The Big Bang Theory Season 12, Episode 17
"And the absence of side effects means that Inflaminex

The Big Bang Theory Season 6, Episode 8
Who cares what stupid 43 means?

Game of Thrones Season 2, Episode 7
Do you know what legacy means?